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目前,外用抗真菌药分软膏、乳膏及液体药剂两类.其中,软膏、乳膏因在皮肤上的贮留性强,刺激性小,使用方便,故临床应用广泛.至于液体药剂,如依据皮肤症状选择使用,也是临床常用剂型.另一方面,近年来咪唑类衍生物相继被开发.它们具有最广泛的抗菌谱.除能治疗白癣外,对卡他性皮炎,白癜风等真菌性疾患疗效较好.其中硝酸醋苯苄肟唑是1975年由瑞士Siegfried公司合成,Roche公司开发的新型咪唑类抗真菌药.在日本已有1%
At present, topical antifungal agents are divided into ointment, cream and liquid medicament, of which ointment and cream have a wide range of clinical applications due to their strong retention on the skin, little irritation and easy to use. As for liquid medicaments, On the other hand, imidazole derivatives have been developed in recent years.It has the most extensive antimicrobial spectrum.In addition to the treatment of white ringworm, the fungal activity of catarrhal dermatitis, vitiligo and other Which has better curative effect, among which, Benbenoxime is the new imidazole antifungal drug developed by Siegfried in Switzerland in 1975 and has been developed in Japan by 1%