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作者复习了现有的各种研究皮质类固醇致皮肤萎缩作用的方法后认为均不理想,因为人皮肤有发展完善的乳头层和微血管系统,实验动物的资料不能简单地应用到人体;在人体试验还应是无损伤性的,并能同时试验比较几种制剂,而本文采用的方法可以满足这些要求。Duhring 小室是一种铝制品,容积0.1毫升,直径12毫米,在一侧前臂可以同时安放6个。涂药后用它们外加有孔胶布封包,每周
The authors reviewed various existing methods for studying skin atrophy caused by corticosteroids and found that they are not ideal because human skin has a well developed papillary layer and microvasculature and experimental animal data can not be simply applied to the human body. It should also be non-invasive, and can be tested at the same time comparing several formulations, and the method used in this article to meet these requirements. The Duhring cell is an aluminum product with a volume of 0.1 milliliters and a diameter of 12 millimeters, with six on the forearm at the same time. Apply them after the coating with a hole tape, weekly