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目的 探讨急性脑梗死患者血液流变学及全血细胞25项参数的变化。方法 对131例脑梗死患者和109例健康人进行血液流变学及全血细胞参数检测,并进行比较。结果 患者组除红细胞变形指数外的血液流变学指标、白细胞计数、红细胞计数、血红蛋白含量、平均血小板体积、血小板分布宽度显著高于对照组(P<0.05～0.01);平均红细胞体积、平均红细胞血红蛋白含量、血小板计数和红细胞变形指数显著低于对照组(P<0.05～0.01),而平均红细胞血红蛋白浓度和红细胞分布宽度与对照组比较无显著性差异(P>0.05)。结论 血液流变学及血细胞参数异常可能与脑梗死的发生有关。
Objective To investigate the changes of hemorheology and 25 parameters of whole blood cells in patients with acute cerebral infarction. Methods Hemorheology and whole blood cell parameters were measured in 131 patients with cerebral infarction and 109 healthy people, and compared. Results Hematological parameters, white blood cell count, erythrocyte count, hemoglobin content, mean platelet volume and platelet distribution width were significantly higher in patients than those in control group (P <0.05 ~ 0.01). Mean erythrocyte volume, mean erythrocyte The hemoglobin content, platelet count and erythrocyte deformability index were significantly lower than those in the control group (P <0.05-0.01). However, the mean erythrocyte hemoglobin concentration and erythrocyte distribution width had no significant difference compared with the control group (P> 0.05). Conclusion Hemorheology and abnormal blood cell parameters may be related to the occurrence of cerebral infarction.