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单侧忽视症通常被认为是一种空间注意定向机制的障碍,一般由右半球的顶叶皮层受损所致。近期的认知神经心理学研究证据显示,单侧忽视的症状涉及多重行为与认知能力紊乱,与注意定向、探索性运动行为和空间工作记忆相互作用的功能障碍有关。脑损伤、经颅磁刺激(TMS)和神经成像等技术的研究证据也显示,右半球的顶下叶、颞-顶交界区和颞上回都是单侧忽视症病人受损的关键脑区。这些脑区功能的同时受损可以解释单侧忽视多重功能障碍的神经机制。
Unilateral neglect is often considered a disorder of the spatial attentional orientation mechanism and is generally caused by impaired parietal cortex in the right hemisphere. Recent evidence of cognitive neuropsychological research shows that the unilateral neglect symptoms involve multiple behaviors and cognitive disturbances and are associated with dysfunctions of attention-seeking, exploratory motor behavior and spatial working memory interactions. Evidence from studies of brain damage, TMS and neuroimaging also shows that the inferior parietal lobe, the temporal-parietal junction and the superior temporal gyrus in the right hemisphere are all key brain regions impaired by unilateral neglect . The simultaneous impaired functioning of these brain regions can explain the neural mechanism of unilateral neglect of multiple dysfunctions.