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目的 分析优质护理对机械通气治疗肺结核合并呼吸衰竭患者应用效果。方法 选取本院2019年3月至2020年3月收治的76例肺结核合并呼吸衰竭患者开展本次试验研究，分组方式选取随机数字表法，将所有患者均分为对照组和观察组两组，每组38例。给予对照组常规护理，给予观察组优质护理，比较两组患者的护理效果。结果 观察组患者SAS评分干预前为（58.35±4.12）分，干预后为（30.25±3.33）分，SDS评分干预前为（54.35±3.65）分，干预后为（28.35±4.11）分，干预前后的PaO_2指标分别为（“,”Objective To analyze the effect of high-quality nursing on mechanical ventilation in the treatment of patients with pulmonary tuberculosis complicated with respiratory failure.Methods A total of 76 patients with pulmonary tuberculosis and respiratory failure who were admitted to our hospital from March 2019 to March 2020 were selected to carry out this trial.Group of 38 cases.The control group was given routine nursing，the observation group was given high-quality nursing，and the nursing effects of the two groups were compared.Results The SAS score of the observation group was(58.35±4.12)before the intervention，(30.25±3.33)after the intervention，and the SDS score was(54.35±3.65)before the intervention and(28.35±4.11)after the intervention.The PaO_2 indexes were(50.12±7.57)mm Hg and(95.25±9.46)mm Hg，and the PaCO_2 indexes were(67.76±5.65)mm Hg and(34.01±4.65)mm Hg，respectively.The SAS score of the control group before the intervention was(58.65)±4.35)points，after intervention(41.35±5.32)points，SDS score before intervention was(54.74±3.12)points，after intervention was(38.36±4.32)points，and PaO_2 indexes before and after intervention were(49.98±8.68)mm Hg and(78.65±8.15)mm Hg，PaCO_2 indicators were(67.98±5.15)mm Hg and(46.11±4.87)mm Hg，respectively.The four indicators of the two groups were compared before intervention(t=0.309，P=0.758;t=0.501，P=0.618;t=0.075，P=0.940;t=0.177，P=0.860)，comparison after intervention(t=10.902，P=0.000;t=14.969，P=0.000;t=8.195，P=0.000;t=11.077，P=0.000);compared with the physical function score of the control group(60.35±4.12)，the psychological function score(62.35±4.11)and the social function score(63.45±4.14)，the observation group(80.35±4.14)4.25)points，(82.35±3.32)points，and(83.32±3.65)points were all high，and there was a significant difference between groups(P=0.000).Among the 38 patients in the control group，7 patients were dissatisfied，14 patients were generally satisfied，17 patients were satisfied，and the nursing satisfaction was 81.58%;among the 38 patients in the study group，1 patient was dissatisfied，6 patients were generally satisfied，and 1 patient was satisfied.31 cases，the nursing satisfaction was 97.37%;compared with the control group，the nursing satisfaction in the observation group was significantly higher(χ^2=5.149，P=0.023).Conclusion Giving high-quality nursing to patients with pulmonary tuberculosis complicated with respiratory failure can effectively improve the patient\'s psychological state and blood gas analysis results，improve the quality of life，and achieve satisfactory nursing effects，which has promotion value.