本文对１８３例新生儿红细胞Ｇ－６－ＰＤ缺陷进行分析及部分随访，表明本地区Ｇ－６－ＰＤ缺陷是高胆红素血症的重要原因（高胆红素血症的Ｇ－６－ＰＤ缺陷率为６２．０％）。认为，凡不明原因的新生儿高胆红素血症无论贫血与否均应想到本病，尤其是男婴。高度怀疑本病者如第１次Ｇ－６－ＰＤ活性测定不低，还应复查。窒息、缺氧、感染等可能为诱发Ｇ－６－ＰＤ缺陷的诱因．本文１８３例中无１例发生胆红素脑病。 In this paper, 183 cases of neonatal erythrocyte G-6-PD defect analysis and partial follow-up, indicating that G-6-PD defects in the region is an important cause of hyperbilirubinemia (hyperbilirubinemia G-6- PD defect rate of 62.0%). That no unexplained neonatal hyperbilirubinemia should be aware of this disease, whether anemia or not, especially the baby boy. A high degree of suspicion of the disease, such as the first G-6-PD activity was not low, should also be reviewed. Asphyxia, hypoxia, infection, etc. may be induced by G-6-PD defects. No one of the 183 cases of this bilirubin encephalopathy.