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本文用兔离体黄体细胞培养方法,观察了儿茶酚胺(肾上腺素、去甲肾上腺素、异丙基肾上腺素及多巴胺)和其受体阻断剂心得安及酚妥拉明对黄体细胞孕酮生成的影响。结果表明,本实验所用儿茶酚胺类物质对离体黄体细胞孕酮生成有极明显的刺激作用,β受体阻断剂心得安可显著抑制儿茶酚胺促孕酮生成作用。α受体阻断剂酚妥拉明并不抑制肾上腺素、异丙基肾上腺素,而抑制去甲肾上腺素和多巴胺对黄体细胞孕酮生成的促进作用。提示儿茶酚胺对黄体细胞孕酮生成的影响,可能与肾上腺素能β受体和α受体有关。
In this paper, rabbit luteal cells in vitro culture methods were observed catecholamines (epinephrine, norepinephrine, isoproterenol and dopamine) and its receptor blocker and propranolol phentolamine progesterone progesterone formation Impact. The results show that the catecholamines used in this experiment on the formation of progesterone in vitro luteal cells have a very significant stimulus, β-blocker propranolol can significantly inhibit the progesterone progesterone generation of catecholamines. α-blocker phentolamine does not inhibit epinephrine, isoproterenol, while inhibiting norepinephrine and dopamine on the progesterone prolapse of luteal cells. Tip catecholamines on progesterone production of luteal cells, may be associated with adrenergic beta receptors and alpha receptors.