Objective This study aims to investigate the surgical results of single-stage en bloc resections using a posterior approach for sacral tumors and evaluate its benefit for these tumors.Methods A total of 32 cases involving patients with sacral tumors who were treated with single-stage en bloc resection by posterior approach from April 2004 to January 2010 were reviewed. The patient cohort included 20 males and 12 females. The average patient age was 49.1 years old(range, 18 to 75 years old). Twenty-seven patients suffered from primary sacral tumors, including 17 patients with chordomas, 5 patients with giant cell tumors of the bone, 3 patients with chondrosarcoma, 1 patient with sarcoma of the nerve fibers, and 1 patient with neurofibromatosis. Five patients were diagnosed with sacral metastatic tumors, including 2 cases of breast cancer, 1 case of renal carcinoma, 1 case of thyroid cancer, and 1 case of lung cancer. According to the Frankel grading system, there were 3 Grade B tumors, 4 Grade C tumors, 10 Grade D tumors, and 15 Grade E tumors. Results The operation took 265 min on average(range, 130–360 min), and blood loss was 1676 m L on average(range, 800–1800 m L) during the operation. The follow-up period ranged from 6 months to 6.2 years. All patients had pain prior to operation. Twenty-eight patients experienced complete pain-relief, and 4 patients experienced partial pain-relief after their operations. In all patients, neurological function was improved more than one grade using the Frankel grading system. Up to now, 5 patients experienced local recurrence after operation, and 2 patients were deceased. The remaining patients are still alive without recurrence. Conclusion Single-stage en bloc resection through a posterior approach for sacral tumors is feasible, safe, and effective. It has many advantages, such as controlling local recurrence, thorough decompression of the spinal cord, relieving pain, improving quality of life, and prolonging survival. Objective This research aims to investigate the surgical results of single-stage en bloc resections using a posterior approach for sacral tumors and evaluate its benefit for these tumors. Methods A total of 32 cases involving patients with sacral tumors who were treated with single-stage en The patient cohort included 20 males and 12 females. The average patient age was 49.1 years old (range, 18 to 75 years old). Twenty-seven patients suffered from primary sacral tumors, including 17 patients with chordomas, 5 patients with giant cell tumors of the bone, 3 patients with chondrosarcoma, 1 patient with sarcoma of the nerve fibers, and 1 patient with neurofibromatosis. Five patients were diagnosed with sacral metastatic tumors, including 2 cases of breast cancer, 1 case of renal carcinoma, 1 case of thyroid cancer, and 1 case of lung cancer. According to the Frankel grading system, there were 3 Grade B tumors, 4 Grade C tumors, 10 Grade D tumors, and 15 Grade E tumors. Results The operation took 265 min on average (range, 130-360 min), and blood loss was 1676 m L average (range, 800-1800 m L All follow-up period ranged from 6 months to 6.2 years. All patients had pain prior to operation. Twenty-eight patients experienced complete pain-relief, and 4 patients experienced partial pain-relief after their operations. In all The patients were still alive without recurrence. The Single-stage en bloc resection through a posterior approach for sacral tumors is feasible, safe, and effective. It has many advantages, such as controlling local recurrence, thorough decompression of the spinal cord, relieving pain, improving quality of life, and prolonging survival.