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目的探讨分析尿沉渣联合干化学法检测在泌尿系统肿瘤患者尿路感染中的诊断价值。方法选取2011年2月至2013年2月间收治的84例泌尿系肿瘤患者,其中膀胱癌49例,前列腺癌14例,肾癌11例,肾盂输尿管肿瘤10例。采用UF-100和干化学分析仪检测所有患者清洁中段尿中的白细胞、细菌、白细胞酯酶(LEU)及亚硝酸盐(NIT)。84例患者均进行尿细菌培养,比较结果。结果定量尿细菌培养阳性率为58.3%(49/84)。干化学法检测特异性为93.2%,敏感性为31.2%,与尿细菌培养结果比较,差异有统计学意义(P<0.05)。UF-100尿沉渣分析结果阳性52例,灵敏度为81.8%,特异度为73.3%。尿沉渣分析联合尿干化学法检查结果为阳性44例,阴性40例,特异度为71.9%,灵敏度为93.6%。定量尿细菌培养阳性49例,阴性39例,差异无统计学意义(P>0.05)。结论 UF-100型全自动尿沉渣分析仪联合尿干化学分析仪使用可作为肿瘤患者尿路感染诊断的重要辅助指标,有重要临床意义。
Objective To investigate the diagnostic value of urinary sediment combined with dry chemical method in the diagnosis of urinary tract infection in patients with urinary system tumors. Methods Eighty-four patients with urinary tract tumors admitted from February 2011 to February 2013 were selected, including 49 cases of bladder cancer, 14 cases of prostate cancer, 11 cases of kidney cancer and 10 cases of ureteropelvic cancer. UF-100 and dry chemistry analyzers were used to detect leukocyte, bacterial, leukocyte esterase (LEU) and nitrite (NIT) in the mid-cleansing urine of all patients. 84 patients were urine bacterial culture, the results were compared. Results The positive rate of quantitative urine culture was 58.3% (49/84). The specificity of dry chemical method was 93.2% and the sensitivity was 31.2%, which was significantly different from the results of urine bacterial culture (P <0.05). UF-100 urinary sediment analysis results were positive in 52 cases, the sensitivity was 81.8%, the specificity was 73.3%. Urine sediment analysis combined with urine dry chemical test results were positive in 44 cases, negative in 40 cases, the specificity was 71.9%, the sensitivity was 93.6%. There were 49 cases of positive urine bacterial culture positive and 39 cases negative, the difference was not statistically significant (P> 0.05). Conclusion UF-100 automatic urine sediment analyzer combined with urine dry chemical analyzer can be used as an important auxiliary indicator of urinary tract infection in patients with cancer, has important clinical significance.