论文部分内容阅读
[目的]研究刺梨多糖的药理作用,为资源开发利用提供基础研究资料。[方法]小鼠口服给予刺梨多糖,以人参皂甙为阳性对照,观察刺梨多糖对小鼠游泳时间、常压缺氧、高温及低温环境下存活时间的影响;以及对巨噬细胞吞噬功能和血清溶血素的影响。[结果]刺梨多糖可延长小鼠常压耐缺氧时间、游泳时间、耐高温时间和耐低温时间(与正常对照组比,P<0.05或P<0.01),并能增加小鼠巨噬细胞吞噬鸡红细胞的百分率,提高吞噬指数、延长小鼠血液的半数溶血时(P<0.05或P<0.01)。[结论]刺梨多糖能够显著提高小鼠抗疲劳、耐缺氧、耐高温及耐低温的能力,提高小鼠的免疫能力。
[Objective] The research aimed to study the pharmacological effects of Rosa roxburghii polysaccharides and provide basic research data for resource development and utilization. [Methods] Mice were orally given polysaccharides of Rosa roxburghii, and ginsenosides were used as positive controls to observe the effect of raspasa polysaccharides on swimming time, atmospheric hypoxia, high temperature and low temperature environment survival time of mice, and the phagocytic function of macrophages. And the effect of serum hemolysin. [Results] Polysaccharides of roxburghii could prolong the duration of hypoxia tolerance, swimming time, high temperature resistance and hypothermia tolerance time of the mice (P<0.05 or P<0.01 compared with the normal control group) and increased the macrophages of mice. The percentage of chicken erythrocytes phagocytosed by the cells, the phagocytic index was increased, and the haemolysis of the mouse blood was prolonged (P<0.05 or P<0.01). [Conclusion] Polysaccharides of Rosa roxburghii could significantly improve the ability of mice to resist fatigue, hypoxia, high temperature and low temperature tolerance, and increase the immunity of mice.