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目的:观察盐酸丙卡特罗口服液辅助治疗婴幼儿喘息性支气管炎的临床疗效。方法:选取我院收治的诊断为“喘息性支气管炎”的1~3岁患儿186例,按随机抽样法分为丙卡特罗组65例、沙丁胺醇组61例和对照组60例。对照组给予炎琥宁抗病毒、氨溴索化痰、吸痰等常规对症治疗及孟鲁司特钠咀嚼片每次4 mg,每晚1次口服。丙卡特罗组和沙丁胺醇组分别在对照组治疗基础上加用盐酸丙卡特罗口服液(0.25 mL/kg,每12 h 1次口服)、吸入用硫酸沙丁胺醇溶液(0.03 mL/kg,每12 h 1次雾化吸入)辅助治疗。三组疗程均为5 d。结果:用药5 d后总有效率丙卡特罗组为93.85%,沙丁胺醇组为95.08%,对照组为75.00%,丙卡特罗组和沙丁胺醇组均高于对照组(P<0.01),丙卡特罗组与沙丁胺醇组比较差异无统计学意义(P>0.05)。结论:盐酸丙卡特罗口服液佐治婴幼儿喘息性支气管炎疗效肯定,值得无雾化吸入条件的基层医院推广应用。
Objective: To observe the clinical efficacy of procaterol hydrochloride oral solution in the treatment of infantile asthmatic bronchitis. Methods: A total of 186 children aged 1-3 years old diagnosed as “asthmatic bronchitis” admitted to our hospital were divided into three groups: 65 patients in the procateral group, 61 patients in the salbutamol group, and 60 patients in the control group. Control group were given Yan Hu Ning anti-virus, ambroxol phlegm, suction and other conventional symptomatic treatment and montelukast sodium chewable tablets 4 mg each time, 1 night orally. In the control group, procaterol hydrochloride oral solution (0.25 mL / kg orally once every 12 h) was administered to patients receiving procateral and salbutamol respectively. Patients were treated with salbutamol sulfate (0.03 mL / kg, every 12 h 1 atomized inhalation) adjuvant therapy. Three courses of treatment are 5 d. Results: After 5 days of treatment, the total effective rate in the procateral group was 93.85%, in the salbutamol group was 95.08% and in the control group was 75.00%, both in the procateror and salbutamol groups were significantly higher than those in the control group (P <0.01) There was no significant difference between the group and the salbutamol group (P> 0.05). CONCLUSION: Procaterol Hydrochloride Oral Solution is effective in treating asthmatic bronchitis in infants and young children. It is worth popularizing and applying to the primary hospital which is worthy of inhalation without inhalation.