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近年来,我国临床医师对炎症性肠病(IBD)的诊治水平有了很大提高,但由于儿童和青少年IBD特殊的临床表现,常在误诊多年后才被诊断,失去了早期治疗的机会,给社会和家庭带来沉重负担。本研究就儿童和青少年IBD的临床特点作一综述。一、青少年IBD的流行病学 Crohn报道的第一例克罗恩炳患者(crohn’s disease,CD)是一位16岁男孩。此后的流行病学资料显示CD和溃疡性结肠炎(ulcerative colonitis.UC)患者中,青少年分别占25％～30％和20％。德国约有20万人患IBD,其中6万为儿童和青少年,约40％的患者在十岁前发病。北美有报道显示,儿童和青少年CD的发病率为2.14/1×10~5,UC为4.56/
In recent years, our clinicians have greatly improved the diagnosis and treatment of IBD. However, due to the special clinical manifestations of IBD in children and adolescents, they are often diagnosed only after many years of misdiagnosis, losing the chance of early treatment. To the community and family a heavy burden. This study reviews the clinical features of IBD in children and adolescents. First, the epidemiology of adolescent IBD Crohn reported the first case of Crohn’s Bing patients (crohn’s disease, CD) is a 16-year-old boy. Subsequent epidemiological data show that adolescents account for 25% -30% and 20% of patients with CD and ulcerative colonitis. UC, respectively. About 200,000 people in Germany suffer from IBD, of whom 60,000 are children and adolescents and about 40% of whom are affected by the age of 10. North America has reported that the incidence of CD in children and adolescents was 2.14 / 1 × 10 ~ 5, UC 4.56 /