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氟嗪酸(Ofloxacin简称OFX)是一种新的喹诺酮(Quinolone)类抗菌药物,对下呼吸道感染有特殊疗效,是喹诺酮类抗菌药物中最有发展的药物之一。本文报道用OFX和头孢唑啉治疗40名下呼吸道感染的疗效。其中男13例,女27例,年龄18～73岁(平均57.5±15.9岁),体重47～81kg(平均64.3±12.2kg)。21例服用OFX,每12小时,每次300mg,平均治疗时间为8.33±1.49天。19例肌注头孢唑啉,每12小时,每次1g,平均治疗时间8.42±1.39天。治疗期间同时使用粘痰溶解剂的有22例,可的松18例,抗心律失常药18例。
Ofloxacin (Ofloxacin referred to as OFX) is a new quinolone (Quinolone) antibacterial drugs, has a special effect on lower respiratory tract infection, quinolone antibacterial drugs is one of the most developed drugs. This article reports the efficacy of OFX and cefazolin treatment of 40 lower respiratory tract infections. There were 13 males and 27 females, aged from 18 to 73 years (average 57.5 ± 15.9 years) and weight 47 to 81 kg (average 64.3 ± 12.2 kg). Of 21 patients taking OFX, every 12 hours, each 300mg, the average treatment time was 8.33 ± 1.49 days. 19 cases cefazolin intramuscular injection every 12 hours, each 1g, the average treatment time of 8.42 ± 1.39 days. During the treatment of phlegm dissolving agent used in 22 cases, 18 cases of cortisone, anti-arrhythmic drugs in 18 cases.