目的 :观察 1 2 5 I籽全封闭人工放射性核素放射源植入组织间治疗癌症的疗效 ,方法 :将 1 2 5 I放射源植入到靶组织内治疗 7例恶性肿瘤 ,其中胃癌、肺癌、肝癌、卵巢癌、恶性神经鞘瘤及软骨肉瘤各 1例 ,肠癌 2例。结果 :随访 4～ 10个月 ,7例均取得较满意的近期疗效 ,未发现术后血象明显降低或其他放射损伤症状 ,亦未发现籽脱落或游走等并发症。 结论 :1 2 5 I籽永久性植入治疗癌症效果满意 ,并发症少 ,易于防护 ,有良好的临床应用前景。 OBJECTIVE: To observe the curative effect of intra-arteria l2 5 I seeds fully enclosed artificial radionuclide radioactive source implantation for cancer treatment. Methods: The 125 I radioactive sources were implanted into the target tissues to treat 7 malignant tumors, including gastric cancer, lung cancer , Liver cancer, ovarian cancer, malignant schwannoma and chondrosarcoma in 1 case, 2 cases of intestinal cancer. Results: After 4 to 10 months of follow-up, all the 7 patients were satisfied with the short-term curative effect. No significant postoperative blood loss or other radiation injury symptoms were found. No complications such as exfoliation or wandering of the seeds were found. CONCLUSION: The permanent implant of 125 seeds is satisfactory in the treatment of cancer with few complications and is easy to be protected. It has good clinical application prospect.