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通过使用ＰＡＲＰ酶的抑制剂研究了降低ＰＡＲＰ酶的活性对外源基因转染效率及整合作用的影响，结果表明，转染的外源基因的吸收及瞬时表达不依赖于ＰＡＲＰ酶的活性，而外源基因的整合作用与ＰＡＲＰ酶的活性有关。
The effect of decreasing the activity of PARPase on the efficiency of transfection of exogenous gene and its integration effect was studied by using inhibitor of PARPase. The results showed that the uptake and transient expression of transfected exogenous gene did not depend on the activity of PARPase, The integration of the source gene is related to the activity of PARP enzyme.