Full aero-elastic model tests are carried out to investigate wind-induced vibration of middle steel pylon of Taizhou Bridge. Model of the pylon under different construction periods is tested in both uniform and turbulent flow field. And the yaw angle of wind changes from transverse to longitudinal. Through full aero-elastic model testing, wind-induced vibration is checked, which includes vortex resonance, buffeting and galloping. Vortex resonance is observed and further studies are carried out by changing damping ratio. Based on wind tunnel testing results, wind-resistance of middle pylon is evaluated and some suggestions are given for middle pylon’s construction. Full aero-elastic model tests are carried out to investigate wind-induced vibration of middle steel pylon of Taizhou Bridge. Model of the pylon under different construction periods is tested in both uniform and turbulent flow field. And the yaw angle of wind changes from transverse to longitudinal. Through full aero-elastic model testing, wind-induced vibration is checked, which includes vortex resonance, buffeting and galloping. Vortex resonance was observed and further studies are carried out by changing damping ratio. Based on wind tunnel testing results, wind -resistance of middle pylon is evaluated and some suggestions are given for middle pylon’s construction.