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目的调查分析南京医科大学附属常州第二人民医院2007至2008年甲状腺瘤手术住院患者抗菌药物应用情况及合理性。方法根据事先设计好的调查表,按统一方法和标准,对南京医科大学附属常州第二人民医院2007至2008年间甲状腺瘤手术患者预防使用抗菌药物的情况进行回顾性分析。结果甲状腺瘤手术住院患者抗菌药物总应用率为98.93%。156例为手术后开始应用抗菌药物,预防用药以单独用药为主,二联用药占较小比例;手术后用药时间较长,长于48h的病例占91.35%。结论应该加强甲状腺瘤手术患者抗菌药物的应用管理,依据用药指征、患者疾病特点和细菌耐药情况选择预防用药,避免不必要用药和预防用药时间过长,以减少耐药菌株产生,控制医院感染。
Objective To investigate the application of antimicrobial agents in hospitalized patients with thyroid tumors from 2007 to 2008 in Changzhou Second People’s Hospital Affiliated to Nanjing Medical University and its rationality. Methods According to the pre-designed questionnaire and according to the unified methods and standards, we retrospectively analyzed the preventive use of antimicrobial agents in patients with thyroid tumors during 2007-2008 at the Second People’s Hospital of Changzhou, Nanjing Medical University. Results The total application rate of antibacterials in inpatients with thyroid tumor was 98.93%. 156 cases started to use antimicrobial agents after operation, prophylaxis was mainly used alone, and the two drugs accounted for a small proportion. After the operation, medication took longer, which was 91.35% longer than 48 hours. Conclusion The management of antimicrobial agents in patients with thyroid tumors should be strengthened. Preventive medication should be selected according to the indications of drug use, disease characteristics of patients and drug resistance of bacteria to avoid unnecessary medication and prevention of overdose of drug to reduce the generation of drug-resistant strains and to control the hospital infection.