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目的比较两种不同干预方法对重度子痫前期病史妇女心血管疾病危险因素的影响,为降低其远期心血管疾病的风险提供依据。方法将55例重度子痫前期病史产后1~3年妇女随机分为常规组(26例)和强化组(29例)。常规组行常规饮食和运动指导、开放式咨询;强化组在常规干预基础上按照食物交换份法制定每人每餐饮食方案,每月定期追踪强化。连续干预3个月后评价效果。结果强化组收缩压、体质量、腰围、空腹血糖、总胆固醇/高密度脂蛋白和10年心血管疾病危险分数较干预前显著降低(均P<0.05),常规组收缩压、舒张压较干预前显著降低(均P<0.05)。结论常规和强化干预措施均可改善重度子痫前期病史妇女心血管疾病的危险因素,强化干预措施较常规干预措施更有效。
Objective To compare the effects of two different interventions on risk factors of cardiovascular disease in women with severe preeclampsia and to provide evidence for reducing their risk of long-term cardiovascular disease. Methods Fifty-five women with severe preeclampsia 1-3 years after delivery were randomly divided into routine group (n = 26) and intensive group (n = 29). The routine group was given routine diet and exercise instruction and open counseling. The intensive group developed diet plan per person per meal on the basis of routine intervention according to the law of food exchange, and regularly followed the intensification every month. After 3 months of continuous intervention, the effect was evaluated. Results The systolic blood pressure, body weight, waist circumference, fasting blood glucose, total cholesterol / high density lipoprotein, and 10-year cardiovascular disease risk scores in intensive group were significantly lower than those before intervention (all P <0.05) Before significant reduction (all P <0.05). Conclusion Both conventional and intensive interventions can improve the risk factors of cardiovascular disease in women with severe preeclampsia, and strengthen interventions more effectively than conventional interventions.