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本文对56例癌性胸腔积液患者的血清及胸水测定了其中CEA、β2-MG、SF及CT的含量,以试剂参考正常值为诊断界值。测定结果提示,它们对癌性胸腔积液具有早期诊断意义及鉴别诊断价值;与结核性胸水比较均有显著差异(P<0.005)。作者认为对胸腔积液病人应同时测定胸水及血清中的CEA、β2-MG,以有助于癌性胸水与结核性胸水的鉴别诊断。癌性胸水中CEA、β2-MG、SF的测定值明显高于血清测定值(P<0.001);而CT含量癌性胸水与血清测定值无差异(P>0.005),故认为同时测定血清及胸水CEA、SF、β2-MG对癌性胸水的诊断与鉴别诊断更有意义。
In this paper, serum CEA, β2-MG, SF and CT were measured in serum and pleural fluid of 56 patients with cancerous pleural effusions. The measurement results suggest that they have early diagnostic value and differential diagnostic value for cancerous pleural effusion; there is a significant difference compared with tuberculous pleural effusion (P<0.005). The authors believe that in pleural effusion patients, CEA and β2-MG in pleural effusion and serum should be measured at the same time to help differential diagnosis of cancerous pleural effusion and tuberculous pleural effusion. The measured values of CEA, β2-MG and SF in cancerous pleural fluid were significantly higher than those measured in serum (P<0.001). However, the CT content of malignant pleural effusion and serum had no difference (P>0.005). Serum and pleural effusion CEA, SF, and β2-MG are more significant for the diagnosis and differential diagnosis of cancerous pleural effusion.