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目的观察使用尤瑞克林治疗急性脑梗死的远期疗效。方法入选急性脑梗死患者120例,分为治疗组80例及对照组40例;两组均予以相同剂量的阿司匹林,治疗组加用尤瑞克林0.15 PNA单位加入生理盐水100mL,静滴,两组均2周为1疗程。治疗前和尤瑞克林疗程结束后2周、12周分别测定神经功能缺损(NDS)评分,12周时评定临床疗效。结果与对照组对比,尤瑞克林组治疗2周和12周的NDS评分改善明显,尤瑞克林组治疗12周后总有效率90.00%,对照组77.5%,差异有统计学意义(P<0.05)。结论尤瑞克林能显著改善急性脑梗死的神经功能缺损,提高疗效,安全性高,值得临床推广使用。
Objective To observe the long-term effect of using erilecin in the treatment of acute cerebral infarction. Methods A total of 120 patients with acute cerebral infarction were divided into treatment group (n = 80) and control group (n = 40). Both groups were given the same dose of aspirin. The patients in treatment group were given 100 mL of normal saline Group were 2 weeks for a course of treatment. Neurological impairment (NDS) scores were measured before treatment and after 2 weeks and 12 weeks of treatment with urelin. The clinical efficacy was assessed at 12 weeks. Results Compared with the control group, the scores of NDS in the two groups were significantly improved after 2 weeks and 12 weeks of treatment, the total effective rate was 90.00% in 12 weeks of treatment, and 77.5% of control group, the difference was statistically significant (P <0.05). Conclusion Youre Kelin can significantly improve the neurological deficits in patients with acute cerebral infarction, improve efficacy, high safety, and worthy of clinical promotion.