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In order to study the effect of seismic permanent deformation on the safety and stability of earth-rock dam, the permanent deformation is considered as the non-design permanent load, and the stress-strain hysteresis curve is also considered when the earth is under cyclic load. The research work can make the calculation results of plastic col-lapse more accurate by including the effect of the post-earthquake degree of plastic deformation on the stability of the earth-rock dam, and the dam safety factor decreases from 2.50 to 1.90 after the magnitude-8 earthquake. Moreover, the research work will also improve the design of the earth-rock dam under abnormal operating conditions.