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目的研究探讨恶性肿瘤相关物质在食管癌的早期诊断,早期治疗的临床应用价值。方法利用美国ABBOTYEAR2000型免疫分析系统何该公司试剂盒操作,检测30例食管癌患者,5例其他癌症及20例正常人血清的CEA浓度。结果实验结果表明食管癌与CEA有显著的相关性,食管癌与正常人差异有统计学意义(P<0.01),还可见食管癌分化程度与CEA测定存在差异有统计学意义(P<0.01),在联合检测CEA对食管癌比较诊断敏感性占70%～80%左右。结论CEA的增高与食管肿瘤生长、转移密切相关。也可作为联合检测其他恶性肿瘤的基础标志物的参考指标。
Objective To study the clinical value of early diagnosis and early treatment of malignant tumor related substances in esophageal cancer. Methods The American ABBOTYEAR2000 immunoassay system was used to test the CEA concentration of 30 patients with esophageal cancer, 5 patients with other cancers and 20 normal human serums. Results The results showed that there was a significant correlation between esophageal cancer and CEA. There was significant difference between esophageal cancer and normal people (P <0.01). The difference between esophageal cancer differentiation and CEA was also statistically significant (P <0.01) , In the joint detection of CEA diagnostic sensitivity for esophageal cancer accounted for about 70% to 80%. Conclusions The increase of CEA is closely related to the growth and metastasis of esophageal tumor. It can also serve as a reference index for the joint detection of other malignancies based on the underlying markers.