背景基础及观察性研究曾反映,抗氧化剂,包括维生素E及C可能起预防心血管病的作用。有几项维生素E二级预防临床试验反映其可能降低心血管病发病率。而几项一级预防试验结果大多阴性,其中只有几项观察开始时属低危或平常危险的男性。单用维生素C的远期临床试验很少。虽然远期效果 Background and observational studies have shown that antioxidants, including vitamin E and C, may play a role in the prevention of cardiovascular disease. There are several clinical trials of secondary prevention of vitamin E reflect the possibility of reducing the incidence of cardiovascular disease. However, the results of several primary prevention trials were mostly negative, of which only a few of the men who started the study were those at low risk or usual risk. Long-term clinical trials with vitamin C alone are rare. Although the long-term effect