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一、病毒感染自1962年试用干扰素预防牛痘病毒感染以来,不少研究者将其用于其他病毒感染性疾病之防治。对疱疹病毒,由于开发了无环鸟苷(acyclovir)、阿糖腺苷(Ara-A)等有效的抗病毒剂,因此,适于投用干扰素(IFN)的情况不多。但在急性脑炎、恶性肿瘤化疗过程中的患者、骨髓移植的患者等由疱疹病毒感染转为重症的高危人群,用其预防和治疗的并不少。目前,需用IFN治疗的病毒感染为亚急性硬化性全脑炎(SSPE)及慢性活动性EB病毒感染症。SSPE
First, the virus infection Since 1962 trial of interferon to prevent vaccinia virus infection, many researchers will be used for the prevention and treatment of other viral infectious diseases. Herpes simplex virus is suitable for administration of interferon (IFN) due to the development of effective antiviral agents such as acyclovir and Ara-A. However, in patients with acute encephalitis, malignant tumor chemotherapy, patients with bone marrow transplants and other herpes virus infection in critically ill patients at high risk of prevention and treatment with a lot of them. At present, the viral infections to be treated with IFN are sub-acute sclerosing full-brain disease (SSPE) and chronic active EBV infection. SSPE