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单光子发射断层成像技术在心血管及脑功能疾病的诊断上具有重要的临床意义。本研究以Kunyansky及以前的研究工作为基础,针对平行束探测模式,推导及建立了有效的解析重建算法,可对噪声、散射、衰减及探测器响应进行同时补偿,用于获取SPECT定量快速成像。数字及Monte Carlo仿真实验表明,所提出的定量解析重建算法是可行的,它极大地改善了重建图像的对比度及分辨率,基本消除了图像中的伪迹。该算法在达到迭代算法精度的同时,计算量却大为降低,与常规滤波反投影重建法近似。
Single photon emission tomography has important clinical significance in the diagnosis of cardiovascular and brain function diseases. Based on the Kunyansky and previous research work, this paper deduces and establishes an effective analytical reconstruction algorithm for parallel beam detection mode, which can simultaneously compensate for noise, scattering, attenuation and detector response for acquiring SPECT Quantitative Fast Imaging . Numerical and Monte Carlo simulation experiments show that the proposed quantitative analysis and reconstruction algorithm is feasible. It greatly improves the contrast and resolution of the reconstructed image, and virtually eliminates the artifacts in the image. When the algorithm reaches the accuracy of iterative algorithm, the computational complexity is greatly reduced, which is similar to the conventional filtering backprojection method.