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探讨血压因素在皮质下动脉硬化性脑病白质损害中的作用。患者35例,均有高血压病史。采用动态检测技术观察血压的变化。利用CT机影像密度计法测定大脑白质低密度范围、白质萎缩程度及全脑萎缩程度。对所得血压及CT结果进行单因素相关性分析和逐步回归分析。结果显示,患者脑CT改变与高血压病程、24小时平均收缩压及收缩压波动密切相关,但各项血压指标在不同方程中的贡献率有所不同。大脑白质低密度范围与高血压病程关系最为密切,而脑萎缩程度与血压波动关系最密切。提示长期高血压是造成白质低密度的重要因素,而患者脑实质的丢失主要与血压波动有关。鉴于随测血压未能进入回归方程,所以强调动态监测患者血压。
To investigate the role of blood pressure in white matter damage of subcortical arteriosclerotic encephalopathy. 35 patients, have a history of hypertension. Using dynamic detection technology to observe changes in blood pressure. CT image densitometry was used to determine the range of low density white matter, atrophy of white matter and whole brain atrophy. The obtained blood pressure and CT results were analyzed by single factor correlation and stepwise regression analysis. The results showed that patients with brain CT changes and duration of hypertension, 24-hour average systolic blood pressure and systolic blood pressure fluctuations are closely related, but the various blood pressure indicators in different equations in the contribution rate is different. The low density of white matter of the brain is closely related to the course of hypertension, while the degree of brain atrophy is closely related to the fluctuation of blood pressure. Prompted long-term hypertension is an important factor in the low density of white matter, while the loss of patients with brain parenchyma and blood pressure fluctuations. In view of the measurement of blood pressure failed to enter the regression equation, so the emphasis on dynamic monitoring of patients with blood pressure.