近来,利用鼻腔吸收使药物输送达到全身,对易受消化道和肝脏首过代谢作用的药物尤其对肽类激素,是一种有效的手段,引起了人们的注意。1984年在美国召开了经鼻给药进行全身治疗的国际会议。然而,肽类激素等难吸收性高分子药物进行鼻腔给药时, Recently, the use of nasal absorption to drug delivery to the body, the first susceptible to digestive tract and liver metabolism of drugs, especially for peptide hormones, is an effective means of attracting attention. In 1984, an international conference was held in the United States for nasal administration for systemic treatment. However, in the case of intranasal administration of poorly absorbable macromolecular drugs such as peptide hormones,