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目的探讨参麦注射液合用环磷腺苷治疗难治性心力衰竭的临床疗效。方法82例难治性心力衰竭患者随机分为对照组和治疗组。对照组常规治疗(吸氧、利尿剂、洋地黄、血管扩张剂、血管紧张素转换酶抑制剂(ACEI)、控制感染和对症支持疗法)。治疗组在常规治疗基础上,参麦注射液40 ml加入5%的葡萄糖250 ml,环磷腺苷40 mg加入5%葡萄糖250 ml静脉点滴,2周为1个疗程,比较两组心功能的改善情况。结果治疗组心功能有显著改善(P均<0.05),治疗组与对照组比较有明显差异(P<0.05)。结论参麦注射液合用环磷腺苷治疗难治性心力衰竭疗效明显,安全可靠。
Objective To investigate the clinical efficacy of Shenmai injection combined with cyclic adenosine monophosphate in the treatment of refractory heart failure. Methods 82 patients with refractory heart failure were randomly divided into control group and treatment group. Control subjects received routine treatment (oxygen, diuretics, digitalis, vasodilators, angiotensin-converting enzyme inhibitors (ACEIs), infection control and symptomatic supportive care). The treatment group on the basis of conventional treatment, Shen Mai injection 40 ml added 5% glucose 250 ml, 40 mg of cyclic adenosine monophosphate added 250 ml 5% glucose intravenous drip for 2 weeks for a course of treatment, compared two groups of cardiac function Improve the situation. Results The cardiac function of the treatment group was significantly improved (P <0.05). There was significant difference between the treatment group and the control group (P <0.05). Conclusion Shenmai injection combined with cyclic adenosine monophosphate treatment of refractory heart failure obvious, safe and reliable.