烟雾病是一种进行性双侧颈内动脉末端狭窄或闭塞并在脑基底部出现异常动脉血管网的疾病。其病因尚不明确。在家族性烟雾病中发现基因改变,细胞因子在血管狭窄-闭塞和(或)异常血管网生成的进程中也起作用,许多手术方法,包括直接、间接血管重建及其联合使用可以提高脑缺血患者的脑血流量。进一步深入研究也许可以阐明烟雾病的发病机制及发现对脑出血性烟雾病有效的血管重建手术。 Moyamoya disease is a disease of the progressive bilateral stenosis or occlusion of the internal carotid artery with an abnormal arterial network at the base of the brain. The etiology is not clear. Genetic changes are found in familial moyamoya disease and cytokines play a role in the process of vascular stenosis-occlusion and / or abnormal vascular network formation. Many surgical procedures, including direct and indirect revascularization and their combination, can improve brain deficits Blood of patients with cerebral blood flow. Further study may shed light on the pathogenesis of moyamoya disease and find effective revascularization procedures for cerebral hemorrhagic moyamoya disease.