论文部分内容阅读
目的应用超声造影观察门脉右支开始显影时间以及彩色多普勒流速剖面技术检测门脉右支流速和血流量,以探讨其评价肝硬化程度的临床价值。方法23例乙型病毒性肝炎后肝硬化患者,分为肝硬化代偿组(11例)和肝硬化失代偿组(12例)。非肝硬化患者24例作为对照组。观察门脉右支开始显影时间,并检测门脉右支流速和血流量,分别比较各参数之间差异并进行相关性分析。结果肝硬化组门脉右支开始显影时间较非肝硬化对照组明显延长(P<0.01),平均流速、最高流速以及血流量较对照组明显降低(P<0.01)。肝硬化失代偿组门脉右支开始显影时间较肝硬化代偿组明显延长(P<0.05),平均流速、最高流速以及血流量较肝硬化代偿组明显降低(均P<0.01)。肝硬化患者门脉右支开始显影时间与门脉右支平均流速、最高流速以及血流量之间均存在明显负相关(P<0.05)。结论随着肝硬化程度的加重,门脉右支开始显影时间逐渐延长,流速和血流量逐渐下降,两者之间呈明显负相关性,能较好地反映肝硬化代偿期和失代偿期门脉血流动力学变化情况,对于评价肝硬化程度具有较高的临床价值。
OBJECTIVE: To evaluate the clinical value of detecting the degree of cirrhosis by using contrast-enhanced ultrasound to observe the onset time of right portal vein and color Doppler flow profile to detect the right portal vein branch velocity and blood flow. Methods Twenty - three patients with cirrhosis after hepatitis B were divided into decompensated cirrhosis group (n = 11) and decompensated cirrhosis group (n = 12). Twenty-four non-cirrhotic patients served as control group. The right portal vein began to develop and the right portal vein branch velocity and blood flow were measured. The differences between the parameters were compared and the correlation analysis was made. Results The onset time of right portal vein in cirrhotic patients was significantly longer than that in non - cirrhotic patients (P <0.01). The mean flow rate, maximum flow rate and blood flow were significantly lower than those in the control group (P <0.01). Compared with cirrhosis compensatory group, the development time of right portal vein of decompensated cirrhosis was significantly longer (P <0.05). The average flow velocity, maximum flow velocity and blood flow were significantly lower than those of decompensated cirrhosis patients (all P <0.01). There was a significant negative correlation (P <0.05) between the onset time of right portal branch and the right portal vein mean velocity, peak velocity and blood flow in patients with cirrhosis. Conclusions As the degree of cirrhosis increases, the right portal vein begins to develop, the flow velocity and blood flow decrease gradually, and there is a negative correlation between them. It can well reflect the decompensation and decompensation of cirrhosis Period portal vein hemodynamic changes, for the evaluation of the degree of cirrhosis has a high clinical value.