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目的评价经鼻泪道扩张联合丝裂霉素C(MMC)治疗鼻泪管阻塞的疗效和临床应用价值。方法将60例鼻泪管阻塞患者随机分为丝裂霉素组(A组)和硅胶管组(B组),经鼻泪道扩张后A组局部使用MMC,B组逆行置入硅胶管,随访6个月,观察治疗成功率。结果经鼻泪道扩张联合MMC与逆行置入硅胶管术的疗效差异无统计学意义(P=0.058)。结论经鼻泪道扩张联合MMC治疗鼻泪管阻塞可取得与逆行置入硅胶管术相似的临床疗效,具有操作简便、费用低廉、治疗时间短、创伤小、恢复快等优点。
Objective To evaluate the efficacy and clinical value of nasolacrimal duct dilatation combined with mitomycin C (MMC) in the treatment of nasolacrimal duct obstruction. Methods Sixty patients with nasolacrimal duct obstruction were randomly divided into mitomycin group (group A) and silicone tube group (group B). After expansion of nasolacrimal duct, MMC was used in group A, silicone tube was retrograded in group B, Follow up for 6 months, observe the success rate of treatment. Results There was no significant difference in the curative effect between nasolacrimal duct expansion combined with MMC and retrograde silicone tube insertion (P = 0.058). Conclusion Nasolacrimal duct dilation combined with MMC in the treatment of nasolacrimal duct obstruction can be achieved with retrograde resection of silicone tube surgery similar clinical efficacy, with simple operation, low cost, short treatment time, small trauma, rapid recovery and so on.