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全身皮肤电子束治疗(TSEBT)对蕈样霉菌病和Sezary综合征,或皮肤T细胞淋巴瘤进展期皮肤病变是一种有效的姑息治疗。单用TSEBT可治愈早期皮肤T细胞淋巴瘤和无痛型或典型的Kaposi氏肉瘤(即其疾病局限于表皮或皮肤)。TSEBT的剂量在30Gy以下时,对皮肤T细胞淋巴瘤的控制较差,至少30Gy或以上时才可有高的控制率。TSEBT的剂量为24Gy/6次/周,每次4 Gy时对无痛型、典型的Kaposi氏肉瘤可有好的控制。全身皮肤电子来治疗可有许多不同的方法,这些方法的主要区别在于:1.每周照射次数;2.每次剂量及处方和测定剂量的方法;3.电子源的剂量输出率和源皮距;4.电子束的能量和剂量以及加速器
Systemic skin electron beam therapy (TSEBT) is an effective palliative treatment for mycosis fungoides and Sezary syndrome, or advanced skin lesions of cutaneous T-cell lymphoma. TSEBT alone can cure early cutaneous T-cell lymphoma and painless or classical Kaposi’s sarcoma (ie its disease is confined to the epidermis or skin). When the dose of TSEBT is less than 30 Gy, the control of cutaneous T-cell lymphoma is poor, and a high control rate can be achieved when at least 30 Gy or more. The dose of TSEBT is 24 Gy/6 times/week, with 4 Gy each time for good control of painless, typical Kaposi’s sarcoma. There are many different methods for the treatment of systemic skin electrons. The main differences between these methods are: 1. The number of weekly irradiation; 2. The method of each dose and prescription and dose measurement; 3. The dose output rate and source skin of electron source. 4. Electron beam energy and dose and accelerator