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幽门螺杆菌(Helicobacter pylori,Hp)致胃粘膜癌前期病变的研究,若采用纵向随访方法,不但费时费力,而且方法不易规范,很难得出正确结果。我们采用考古学横断研究方法,对相对自然人群,进行内镜活检病理检查,以期探讨Hp感染致胃粘膜癌前期病变的演变规律。 1 材料和方法 1.1 材料凡在我院进行内镜检查的各种慢性胃病患者,除了残胃外,不论住院还是门诊患者均作为研究对象。共计342例。 1.2方法进行内镜检查,分别在胃窦和胃体各钳取2块粘膜,分装两瓶,每瓶制作一个标本,切成10个切片,分别进行HE和Giemsa染色。将仅在胃窦部检出Hp的44例患者归为胃窦组;将在胃窦胃体均检出Hp的180例患者归为胃窦胃体
The study of gastric precancerous lesions caused by Helicobacter pylori (Hp) is not only time-consuming and labor-intensive, but also it is not easy to be standardized. It is difficult to obtain correct results. We use archaeological transversal research methods to conduct endoscopic biopsy pathological examination of relatively natural populations in order to explore the evolution of gastric precancerous lesions caused by Hp infection. 1 Materials and Methods 1.1 Materials All patients with chronic gastropathy who underwent endoscopy in our hospital, except for residual stomach, were hospitalized and outpatients. A total of 342 cases. 1.2 Methods Endoscopic examination, respectively, in the antrum and gastric body clamps to take two mucosa, respectively, two bottles, each bottle made a specimen, cut into 10 sections, were HE and Giemsa staining. Forty-four patients with Hp detected only in the gastric antrum were classified as antrum group; 180 patients with Hp detected in gastric antrum were classified as gastric antrum.