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目的探讨老年原发性高血压病患者颈动脉内膜中层厚度与血清胆红素水平的关系。方法选择老年高血压病患者141例,按颈动脉超声检测结果分内膜增厚组、斑块形成组、管腔狭窄组,同时检测三组患者的血清胆红素水平,并进行统计学分析。结果颈动脉粥样硬化程度越严重,血清总胆红素、直接胆红素和间接胆红素水平越低,三组间比较差异显著(P<0.05)。结论老年高血压病患者的血清胆红素水平变化与动脉粥样硬化关系密切。
Objective To investigate the relationship between carotid artery intima-media thickness and serum bilirubin level in elderly patients with essential hypertension. Methods A total of 141 elderly patients with essential hypertension were enrolled in this study. Serum bilirubin levels in three groups were measured according to the results of carotid artery ultrasonography in terms of intimal thickening, plaque formation and stenosis group, and statistical analysis was performed . Results The severity of carotid atherosclerosis was more serious. The levels of serum total bilirubin, direct bilirubin and indirect bilirubin were lower in three groups (P <0.05). Conclusion Serum bilirubin levels in elderly patients with hypertension are closely related to atherosclerosis.