1病例介绍患者男,62岁,因“四肢无力及肌肉萎缩10+年”于2011年3月收入我科。患者于1994年开始出现双下肢痛性痉挛和双侧乳房发育如女性,并伴有腹部肌肉不自主跳动。1999年患者出现下蹲后站立困难,逐渐缓慢加重,不能自行站立,持拐能缓慢步行。2005年患者出现双肩抬举困难,持握重物力量下降,以左侧为重,日常活动明显受影响,且发现双手虎 1 case description Male patient, aged 62, because “limb weakness and muscle atrophy 10 + years ” in March 2011 income in our department. Patients developed bilateral lower extremity cramps and bilateral gynecomastia in 1994 with involuntary abdominal muscle beating. 1999 patients standing squat after standing difficulty, gradually slowed down, can not stand on their own, holding the abdomen can walk slowly. In 2005, patients had difficulty lifting their shoulders and holding down the weights of heavy objects. Taking the left as their focus, their daily activities were obviously affected and the two-handed tigers