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目的研究彩色多普勒超声联合血清肿瘤标记物糖蛋白抗原(CA)125及CA199对卵巢癌的诊断价值。方法 176例卵巢肿瘤患者,将其依据肿瘤良、恶性划分为A组150例和B组26例,比较两组CA199、CA125、超声评分及血流阻力指数(RI)的差异。结果 B组超声评分为(9.54±1.34)分,高于A组的(4.01±1.13)分,差异有统计学意义(P<0.05);B组RI值低于A组,差异有统计学意义(P<0.05);B组CA199及CA125水平高于相比于A组,差异有统计学意义(P<0.05)。结论针对卵巢癌患者,对其采用彩色多普勒超声联合血清标志物CA125及CA199实施检查,就筛选及诊断卵巢恶性肿瘤具有重要的价值。
Objective To investigate the diagnostic value of color Doppler ultrasonography combined with serum tumor markers glycoprotein antigen (CA) 125 and CA199 in ovarian cancer. Methods One hundred and seventy-six patients with ovarian tumors were divided into two groups according to the tumor grade and malignancy: 150 cases in group A and 26 cases in group B. The differences of CA199, CA125, ultrasonic score and blood flow resistance index (RI) between the two groups were compared. Results The ultrasound score of group B was (9.54 ± 1.34) points higher than that of group A (4.01 ± 1.13), the difference was statistically significant (P <0.05). The RI of group B was lower than that of group A, the difference was statistically significant (P <0.05). The levels of CA199 and CA125 in group B were significantly higher than those in group A (P <0.05). Conclusions Ovarian cancer patients with ovarian cancer by color Doppler ultrasound combined with serum markers CA125 and CA199 implementation of screening, screening and diagnosis of ovarian cancer has important value.