目的:探讨救脑化瘀汤治疗外伤性颅内血肿的疗效及药效作用机理.方法:对126例外伤性颅内血肿患者在常规治疗的同时,应用中药救脑化瘀汤口服或鼻饲,并随机抽取同期住院非手术治疗的外伤性颅内血肿118例作为对照.经头颅CT扫描动态观察颅内血肿的吸收时间,用经颅多普勒(TCD)测定两组病例的脑血流动力学变化.对部分病例进行颅内压监测和临床观察两组病人用药前后的症状、体征的变化.结果:应用救脑化瘀汤组,颅内压有不同程度的降低,颅内血肿吸收时间缩短,脑血流灌注量增强,临床神经系统症状明显改善.结论:在外伤性颅内血肿的非手术治疗中,常规运用脱水,激素,脑代谢活化剂,钙离子拮抗剂的同时,早期应用救脑化瘀汤,可协同疗效,促进脑神经功能恢复,减少并发症,提高生存质量.“,”Objective:To research the curative effect and mechanism of action of “Jiunao Huayu Tang” in the treatment of trauma-induced intracranial hematoma. Methods: While 126 patients with trauma-induced intracranial hematoma were treated by routine, and received concurrently traditional Chinese medicine “Jiunao Huayu Tang” per os or via nasal feeding; 118 pateents, who were in-patient in the same period, with trauma-induced intracranial hematoma which were treated by non-operation as controlled group. Results: In the treatment group, the intracranial pressures were decreased to the various extent, the absorption time of intracranial hematoma was shortened, the perfusion volume of cerebral blood flow was increased, and clinical symptoms in nerve system have been improved significantly. Conclusion: While the routine dehydration was applied and steroids, cerebral metabolic activation a-gents, and calcium antagonist were used in the tranma-induced intracranial hematoma treated by non-operation, the cerebral nerve function would been recovered in the early application of “Jiunao Huayu tang”, the complications were decreased, and patients life quality were improved.