CO中毒的临床表现差异很大,对于拟诊病例,一向需以COHb的升高来确诊,但若化验稍有耽延,血中COHb水平就低至很难能与临床表征相符,甚至不能测及。即使CO已从体内明显排除,由于仍然结合在组织中而无法测定CO的作用,或由于后遗缺氧及CO中毒的继发损害,病人仍可处于抑制状态。有人曾由实验证明,血中物理溶解的CO比COHb危害更大。临床表现和对COHb所作化验之间常有差异,足以造成漏诊和治疗不当。高压氧能有效地置换血红蛋白、肌红蛋白及细胞色素系统中的CO,扭转缺氧损害,减轻继发于缺氧和中毒的脑水肿,从而改善神经系统功能。应果断地对拟诊为CO中毒的重危病例进行高压氧治疗,特别是对那些因等待化验而延误诊治的病例,更应及时使用。 CO poisoning clinical manifestations vary widely, for the proposed diagnosis of cases, has always been to increase the COHb to confirm, but if the test a slight delay, the level of COHb in blood is very low to the clinical manifestations is difficult to match, or even can not measure and. Even though CO has been significantly excluded from the body, the patient can remain in an inhibited condition as the effect of CO can not be determined by still being incorporated in the tissue, or due to secondary hypoxemia and subsequent damage by CO poisoning. It has been experimentally demonstrated that the physically dissolved CO in blood is more harmful than COHb. There are often differences between clinical manifestations and tests done on COHb that can cause misdiagnosis and misdiagnosis. Hyperbaric oxygen can effectively replace the hemoglobin, myoglobin and cytochromes in the system of CO, reverse hypoxia damage and reduce secondary to hypoxia and poisoning of cerebral edema, thereby improving the nervous system function. Should be decisive for the diagnosis of CO poisoning in critically ill patients hyperbaric oxygen therapy, especially for those who wait for the test delay diagnosis and treatment of cases, should be promptly used.