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目的：视察尿毒症患者血速前后凝血和纤溶状态的变化；方法：测定30例尿毒症患者血透前后血浆D二聚体含量，并与18例健康对照；结果：血透前后血浆D二聚体均显著高于对照组（P＜0．01），血透后较血透前增高（P＜0.05）。结论：维持性血透的尿毒症患者存在高凝状态并发生继发性纤溶过程，透析过程可使这一变化更加明显。
Objective: To investigate the changes of blood coagulation and fibrinolysis before and after blood velocity in patients with uremia. Methods: The levels of plasma D-dimer in 30 patients with uremia before and after hemodialysis were measured and compared with 18 healthy controls. Results: (P <0.01). After hemodialysis, hemodialysis increased compared with that before hemodialysis (P <0.05). CONCLUSIONS: Patients with maintenance hemodialysis have hypercoagulable state and secondary fibrinolysis, and the dialysis process may make this change more apparent.