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目的 :总结发作性运动障碍中PKC的临床特征 ,并对其发病机制加以探讨。方法 :对 8例PKC患者临床表现及实验室资料进行分析。结果 :本组中 8例患者发病年龄 8～ 14岁 ,病程 1～ 10年 ,87%为男性。临床表现均由突发运动诱发 ,由久坐、久立后突然改变体位 ,表现为一侧或双侧不自主肢体舞动、躯干扭动和面部异常运动 ,持续数秒钟自行缓解 ,发作时意识清楚 ,2例EEG轻度异常 ,6例正常EEG中有 2例 2 4h动态脑电图示样放电 ,8例服用少量卡马西平完全控制发作。结论 :PKC是发作性运动障碍中一类疾病 ,以开始运动时出现发作性锥体外系症状为特点 ,发作范围局部或全身 ,是可以治愈的 ,抗癫药治疗效果良好
OBJECTIVE: To summarize the clinical features of PKC in patients with nodomotor dyskinesia and to explore its pathogenesis. Methods: The clinical manifestations and laboratory data of 8 patients with PKC were analyzed. Results: Eight patients in this group had a disease of 8-14 years of age and a duration of 1 to 10 years, 87% of whom were men. Clinical manifestations were induced by sudden movement, from sedentary, a sudden change of position after a long time, manifested as one or both involuntary limb gallbladder, torso torsion and facial abnormalities, sustained a few seconds to ease themselves, the onset of consciousness , 2 cases of mild EEG abnormalities, 6 cases of normal EEG 2 cases of 24 hours dynamic electroencephalogram like discharge, 8 patients taking a small amount of carbamazepine complete control of the attack. CONCLUSION: PKC is a kind of disease in episodic dyskinesia. PKC is characterized by onset of extrapyramidal symptoms when it starts to exercise. The onset of the disease is local or systemic, PKC is curable and anti-epileptic drugs are effective.