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微小RNA(microRNA,miRNA)是一种内源性非编码小RNA,以完全或非完全互补的方式与其靶mRNA相结合,调节mRNA表达,从而影响其生物学特征,参与许多肿瘤发生过程。综述血miRNA在女性生殖系统疾病中的研究进展,包括miRNA在女性生殖系统疾病中的表达检测,miRNA与女性生殖系统疾病的发生、分化的相关性及其机制,以及miRNA在女性生殖系统疾病预后判定、治疗等方面的探索。
MicroRNAs (miRNAs) are small, endogenous, non-coding RNAs that bind to their target mRNAs either completely or not completely complementary to regulate mRNA expression, thereby affecting its biological characteristics and participating in many oncogenesis processes. This review summarizes the progress of research on miRNAs in female reproductive system diseases, including the expression and detection of miRNAs in female reproductive system diseases, the correlation and mechanism of miRNAs with the occurrence and differentiation of female reproductive system diseases, and the prognosis of female reproductive system diseases Judgment, treatment and other aspects of exploration.