现代中医药学药性中标有“大、小毒”等的药物可对人体和病人造成危害 ,因药物及病人体质不同 ,所产生的侵害方式及后果亦有差别。1　中药毒性的起源西周时已有专业的医师“聚毒药以供医事”[1] 之说。南北朝时期 ,雷学攴著《炮炙论》叙述各种药物通过适宜的炮炙 ,可以提高药效 Drugs labeled as “big and small poisons” in modern Chinese medicine can cause harm to humans and patients. Because of different drugs and patient’s constitution, there are differences in the methods and consequences of infringement. 1 The Origin of the Toxicity of Traditional Chinese Medicine During the Western Zhou Dynasty, there were already professional doctors who “gather poisons for medical purposes”[1]. During the period of the Southern and Northern Dynasties, Lei Xuezhuan wrote “The Art of Firecrackers” to describe various drugs that can improve drug efficacy through appropriate artillery fire.