消胆胺和降脂2号树脂(Colesterel)均为不吸收的阴离子交换树脂,主要用于降低Ⅱ型高脂蛋白血症患者的胆固醇浓度。胆汁酸与树脂形成不溶性复合物,从而增加其从粪便中排泄。同样某些药物也可与此类制剂络合,以致药物不被吸收或使其吸收大大减少。双氢克尿塞常用于同时使用某种树脂的病人,故对其吸收进行了研究。6名受试者单独应用双氢克塞(75mg 口 Both cholestyramine and Colesterel are non-absorbing anion exchange resins and are used primarily to reduce cholesterol levels in patients with type II hyperlipoproteinemia. Bile acids form insoluble complexes with the resin, increasing their excretion from the feces. Similarly, some drugs can also be complexed with such preparations, so that the drug is not absorbed or its absorption greatly reduced. Hydrochlorothiazide is commonly used in patients who use a certain type of resin at the same time, so their absorption has been studied. Six subjects were treated with bicortatone alone (75 mg mouth