亚硫酸氢钠穿心莲内酯是中国药典1977年版收载的一种抗菌消炎药物,结构为Ⅰ,它是由穿心莲内酯Ⅱ经亚硫酸氢钠加成而制得的。我们在研究穿心莲二萜内酯过程中,鉴于文献中对 NMR 数据未见有较完整的报道,故采用双共振和溶刺效应技术对其中四种已知二萜内酯及其衍生物的 NMR 谱进行了一系列实验研究,初步确定连接官能团的氢质子归属,并找 Sodium bisulfite andrographolide is an antibacterial anti-inflammatory drug that was collected in the 1977 edition of the Chinese Pharmacopoeia and has a structure of I. It is produced by the addition of andrographolide II to sodium bisulphite. In our study of the diterpene lactones of Andrographis paniculata, NMR of two known diterpene lactones and their derivatives was studied using the double resonance and anticoagulant effect techniques given that there was no complete report on the NMR data in the literature. A series of experimental studies were conducted to determine the hydrogen proton attribution of the linking functional group and find