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人类T淋巴细胞白血病病毒Ⅰ型和Ⅱ型(HTLV-Ⅰ/Ⅱ)是一种C型逆转录病毒,主要侵染T淋巴细胞,引起成人T淋巴细胞白血病(ATL)以及热带下肢痉挛性瘫痪或HTLV-Ⅰ相关脊髓病(TSP/HAM)。近10来年的流行病学调查表明,中国的HTLV流行整体上还处于较低的水平,主要在福建、广东有局部集中的流行地区。自1999～2003年间本组在福建莆田地区调查HTLV Ⅰ/Ⅱ感染情况以来,共检出19例HTLV-Ⅰ阳性者,发现了福建东南沿海湄州湾北岸一带HTLV-Ⅰ高流行。为进一步了解中国东南沿海HTLV-Ⅰ病毒在流行区家庭内的传播特点,作者进行此项研究。
Human T-Lymphocytic Leukemia Virus Type I and Type II (HTLV-I / II) is a C-type retrovirus that infects T-lymphocytes primarily, causing adult T-cell lymphocytic leukemia (ATL) and spastic paralysis of tropical lower extremities or HTLV-I related myelopathy (TSP / HAM). Epidemiological surveys in the past 10 years show that the epidemic of HTLV in China as a whole is still at a relatively low level, mainly in Fujian and Guangdong, with a concentration of endemic areas. 19 cases of HTLV-I positive were detected in HTLV Ⅰ / Ⅱ in the Putian area of Fujian Province from 1999 to 2003. The HTLV-Ⅰ epidemic in the north bank of Meizhou Bay in the southeast coast of Fujian Province was found. To further understand the spread of HTLV-I virus in the endemic areas of southeastern China coastal areas, the authors conducted this study.