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发育中的胎儿和儿童易受到某些药物和环境中有毒物质的影响,干扰生长发育,是环境暴露的脆弱人群。儿童对环境毒物的吸收、分布、代谢不仅受基因影响,还与发育年龄密切相关。从对儿童生长发育影响的结局来看,环境暴露的时机非常重要。在胚胎期或胎儿期,存在一些很窄的时间段--即器官形成的高度易感期称为“暴露窗口期”。然而,目前关于出生后环境暴露的易感窗口期的研究还很少,许多环境暴露对儿童的影响存在不确定性。因
Developing fetuses and children are vulnerable to certain drugs and toxic substances in the environment, interfere with the growth and development, and are vulnerable to environmental exposure. Children’s absorption of environmental toxicants, distribution, metabolism is not only affected by genes, but also closely related to the age of development. From the outcome of children’s growth and development of view, the timing of environmental exposure is very important. In the embryonic or fetal period, there are some very narrow periods of time - the highly susceptible phase of organ formation is called the “window of exposure.” However, little is known about the window of susceptibility to post-natal environmental exposure and the impact of many environmental exposures on children is uncertain. because