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目的：探讨艾滋病病毒相关性原发性脑淋巴瘤放射治疗的疗效。方法：从 １９９５年１月至 １９９９年 １２月法国巴黎第十二大学Ｈｅｎｒｉ Ｍｏｎｄｏｒ医院放疗科共收治艾滋病病毒相关性原发性脑淋巴瘤病人８例，均为男性，中位年龄为３２岁（２１～５７岁）。８例病人均接受全脑照射３０ Ｇｙ，后有４例缩野照射原发肿瘤 １５～２０ Ｇｙ，中位照射剂量为 ３７ ．５ Ｇｙ。所有病人均未接受化疗。结果：放疗结束时，肿瘤缩小４例，肿瘤无变化 ３例，肿瘤增大 １例；病人对急性放射反应耐受性尚好。病人中位生存期为７．１个月（３～１９个月）。结论：艾滋病病毒相关性原发性脑淋巴瘤病人的预后差，而放射治疗可在一定程度上延长病人的生存期。
Objective: To investigate the efficacy of radiation therapy for HIV-associated primary brain lymphoma. METHODS: From January 1995 to December 1999, 8 patients with HIV-related primary brain lymphoma were admitted to the Radiotherapy Section of Henri Mondor Hospital, the 12th University of Paris, France. All were male, with a median age of 32 years 21 ~ 57 years old). All 8 patients underwent whole-brain irradiation at 30 Gy. After that, 4 cases contracted the primary tumor from 15 to 20 Gy and the median dose was 37. 5 Gy. All patients did not receive chemotherapy. Results: At the end of radiotherapy, the tumor was reduced in 4 cases, the tumor did not change in 3 cases and the tumor was increased in 1 case. The patient was well tolerated by acute radiation. The median survival time was 7.1 months (3 to 19 months). Conclusion: The prognosis of patients with HIV-related primary brain lymphoma is poor, and radiotherapy can prolong the survival of patients to some extent.