中性粒细胞和单核细胞的成熟、活化、增殖及趋化性主要由细胞因子调节.这些细胞因子有集落刺激因子(CSF)及其它淋巴因子等.在肠粘膜内产生的细胞因子有助于加快中性粒细胞和单核细胞转移至肠炎疾病(IBD)的病损部位,并激活这些炎症细胞.该文对14名肠炎患者和组织学正常对照组的结肠组织中提取的单个核细胞产生细胞因子的情况进行了研究.实验结果表明,IBD患者结肠粘膜单个核细胞产生较高的CSF活性(1402±252u/ The maturation, activation, proliferation and chemotaxis of neutrophils and monocytes are mainly regulated by cytokines, such as colony stimulating factor (CSF) and other lymphokines, etc. The cytokines produced in the intestinal mucosa are helpful To speed up the transfer of neutrophils and monocytes to the lesion site of inflammatory bowel disease (IBD), and to activate these inflammatory cells.In this paper, 14 patients with colitis and histological normal control group extracted from the colon tissue of mononuclear cells The production of cytokines were studied.The experimental results show that IBD patients colonic mucosal mononuclear cells produce higher CSF activity (1402 ± 252u /