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目的:观察祛痰定喘汤治疗COPD急性加重期的临床疗效。方法:将90例COPD急性加重期患者随机分为治疗组(常规西药+祛痰定喘汤治疗)、对照组(常规西药治疗)各45例,比较两组患者的临床疗效、住院时间、中医证候评分及肺功能情况。结果:经过治疗,治疗组患者总有效率为95.6%,对照组患者总有效率为75.6%,差异具有统计学意义(P<0.01)。治疗组患者临床治疗时间显著短于对照组,肺功能指标显著优于对照组,差异具有统计学意义(P<0.05)。治疗组患者治疗后中医证候评分显著低于对照组,差异具有统计学意义(P<0.05)。结论:祛痰定喘汤治疗COPD急性加重期疗效肯定,安全性高,值得临床推广应用。
Objective: To observe the clinical efficacy of expectorant Dingchuan Decoction in the treatment of acute exacerbation of COPD. Methods: Ninety patients with acute exacerbation of COPD were randomly divided into treatment group (conventional western medicine + expectorant Dingchuan Decoction) and control group (conventional western medicine), 45 cases each. The clinical curative effect, length of hospital stay, Syndrome rating and lung function. Results: After treatment, the total effective rate was 95.6% in the treatment group and 75.6% in the control group, the difference was statistically significant (P <0.01). The clinical treatment time of the treatment group was significantly shorter than that of the control group, and the pulmonary function indexes were significantly better than those of the control group, the difference was statistically significant (P <0.05). After treatment, the score of TCM syndrome in treatment group was significantly lower than that in control group, with statistical significance (P <0.05). Conclusion: Expectorant Dingchuan Decoction in the treatment of acute exacerbation of COPD sure effect, high safety, it is worthy of clinical application.