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目的调查丙型病毒性肝炎(HCV)患者生活质量,观察认知行为干预对患者生活质量的影响,为慢性传染性疾病的治疗提供依据。方法选取2011年6月至2013年9月首次在本院就诊,并根据流行病史、病毒学及肝脏血清学检查明确诊断为慢性丙型病毒性肝炎的86例患者作为研究对象,将患者应用随机数字表分为干预组46例和对照组40例。对照组给予抗病毒治疗并规律门诊随访;干预组在此基础上,通过多种形式对患者进行12周的认知行为干预,内容包括加强对疾病的认识、增强战胜疾病的信念及培养良好的生活习惯等。用世界卫生组织(WHO)制定的生存质量测定简易量表(WHOQOL-bref)评价HCV患者的生活质量,并对干预效果进行评价。结果不同社会经济背景及不良生活习惯可影响HCV患者的生活质量,干预组患者的生活质量评分[(57.91±1.67)分]明显高于对照组[(56.99±2.22)分],差异有统计学意义(P<0.05),尤其是在社会关系领域[(15.45±1.14)分]和心理领域[(15.10±0.79)分]较对照组[分别为(14.58±1.43)、(14.69±0.967)分]有明显改善,差异有统计学意义(P<0.05)。结论给予HCV患者认知行为干预能改善其生活质量,为其他慢性感染性疾病的管理模式进行了有效的探索。
Objective To investigate the quality of life of patients with hepatitis C virus (HCV), and to observe the impact of cognitive and behavioral interventions on the quality of life of patients and provide the basis for the treatment of chronic infectious diseases. Methods The first time in our hospital from June 2011 to September 2013 was selected and 86 patients with chronic hepatitis C were diagnosed according to epidemiological history, virology and liver serology. The patients were randomized The digital table is divided into intervention group 46 cases and control group 40 cases. The control group was treated with antiviral therapy and regular outpatient follow-up. On the basis of this, the intervention group conducted cognitive and behavioral interventions for 12 weeks in various forms, which included strengthening the understanding of the disease, enhancing the belief of defeating the disease and cultivating good Living habits and so on. Quality of life of patients with HCV was evaluated by WHOQOL-bref, and the effect of intervention was evaluated. Results The socioeconomic background and adverse lifestyle affect the quality of life of HCV patients. The quality of life score of patients in intervention group [(57.91 ± 1.67) points] was significantly higher than that of control group [(56.99 ± 2.22) points], the difference was statistically significant (15.45 ± 1.14) and psychology [(15.10 ± 0.79) points respectively) compared with the control group [(14.58 ± 1.43) and (14.69 ± 0.967) points respectively (P <0.05) ] Had a significant improvement, the difference was statistically significant (P <0.05). Conclusion Cognitive and behavioral intervention in patients with HCV can improve their quality of life and effectively explore the management of other chronic infectious diseases.